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Journal Of Clinical Oncology Publishes Study Demonstrating Improvement In Overall Response And Progression-Free Survival-Chronic Lymphocytic Leukemia
Cephalon, Inc. (Nasdaq: CEPH) announced yesterday that the Journal of Clinical Oncology has published data from a pivotal phase 3 study demonstrating that TREANDA® (bendamustine HCl) for Injection improved clinical outcomes when compared to chlorambucil in patients with chronic lymphocytic leukemia (CLL). Results of this study were the basis of the March 2008 U.S. Food and Drug Administration (FDA) approval of TREANDA for CLL, the first agent approved by the FDA for this disease since 2001. According to the American Cancer Society, there will be more than 15,000 new cases of CLL diagnosed in 2009 alone. The study results were published online today and will also appear in the print edition later this year.
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AVEO's Tivozanib Demonstrates Anti-Tumor Activity In Engineered Lung Tumors Exhibiting Treatment Resistant Mutations
AVEO Pharmaceuticals, Inc., a biopharmaceutical company leveraging breakthrough discoveries in cancer biology to discover, develop and commercialize targeted oncology therapies, today announced data which demonstrates that tivozanib (AV-951) - the company"s oral, triple VEGF receptor inhibitor - exhibits potent anti-angiogenic and anti-tumor activity in AVEO"s proprietary in vivo lung cancer models. Specifically, treatment with tivozanib resulted in complete tumor growth inhibition or tumor regression (shrinkage) in lung tumors driven by EGFR or KRAS mutations, which are especially difficult to treat. These data are being presented today at the 13th World Conference on Lung Cancer (WCLC) in San Francisco, abstract number PD10.1.5.
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Camp For Children With Hearing Loss And Their Families Offers Weekend Of Fun
The House Ear Institute, HEI, established Family Camp 24 years ago as a comfortable, open forum where parents raising a child with hearing loss could share their experiences and exchange information and varying philosophies with one another.
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Also In Global Health News: HIV Prevention In African Women; SIV In Chimps; Aid, Climate Partnerships; Obstetric Fistula

Reuters Examines Upcoming HIV Prevention Trial In Africa Reuters examines plans for an upcoming HIV prevention trial of women living in Africa. The study, conducted by the U.S-funded Microbicide Trials Network, will help "determine whether some of the antiretroviral (ARV) medicines used to treat HIV can also be used to prevent the disease when given as a vaginal microbicide gel or as an oral tablet taken once daily" as well as which preventative measures women prefer. Mike Chirenje, protocol co-chair of the study told Reuters, "We think [this study is] very unique because nobody has really tested the difference between an oral route of prevention compared to a vaginal route of prevention" (Roelf, 7/22). Chimpanzees Can Get Ill From HIV-Like Virus, Study Finds A Nature study published on Thursday overturns a "decade-old consensus that chimpanzees cannot fall ill as a result of infection with a virus similar to HIV," Nature News reports. "The results suggest that it will not be possible to find the key to HIV immunity in the chimpanzee genome, as scientists had hoped," writes Nature News, adding that it does set "the stage for researchers to gain insight into how HIV and SIV cause disease in their hosts by studying the responses of different primates to the viruses" (Hayden, 7/22). IRIN Examines Aid, Climate Partnerships IRIN examines new partnerships between aid agencies and meteorological services that aim to prevent and respond to disasters in West Africa. Maarten van Aalst, associate director of the International Federation of the Red Cross and Red Crescent regional climate centre in the Senegalese capital, Dakar, said, "The question is not why meteorological services and humanitarian organizations are talking to each other today, but why they have not been talking for one-and-a-half centuries." The article includes examples of collaboration and analyzes the barriers to partnership (7/22). Malawi"s Daily Times Examines Obstetric Fistula The Daily Times examines obstetric fistula in Malawi. The article includes details about women who have dealt with the childbirth complication, which is treatable. It also describes a local education program that aims to teach women about fistulas and improve maternal health (Kasawala, 7/22). This information was reprinted from globalhealth.kff.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Global Health Policy Report, search the archives and sign up for email delivery at globalhealth.kff.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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