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UCSF And Abbott Launch Viral Discovery Center At Mission Bay
The University of California, San Francisco, has partnered with Abbott, a global health care company, to launch a first-of-its kind, non-profit viral diagnostics center near the UCSF Mission Bay campus to help identify unknown viruses from around the world.
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Extending The Life Of An Appetite-Suppressing Peptide
The peptide alpha-MSH works in a region of the brain known as the hypothalamus to suppress appetite. A team of researchers, at Yale University School of Medicine, New Haven, and the University of California Davis, has provided new insight into the way in which levels of the active form of alpha-MSH are regulated in mice. Specifically, genetic and biochemical analysis performed by the team, led by Sabrina Diano and Craig Warden, indicated that the protein PRCP is expressed in the hypothalamus and breaks down the active form of alpha-MSH, generating a slightly smaller peptide that does not suppress food intake. Importantly, administration of PRCP inhibitors to both normal and obese mice reduced their food intake. Further, mice lacking PRCP had increased levels of the active form of alpha-MSH in the hypothalamus and were leaner and shorter than normal mice; they also did not get obese when fed a high-fat diet. The authors suggest that these data are the first step in identifying PRCP as a candidate drug target for the treatment of obesity and obesity-related disorders. Although Richard Palmiter, at the University of Washington, Seattle, also raises this intriguing possibility, he cautions that any drug would need to penetrate the brain.
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New Study Indicates Radiologists Need Standards To Ensure Optimal Visual Accuracy
Radiologists, like professional pilots for example, depend on good vision as part of their occupation. However, radiologists unlike pilots are not required to undergo regular vision testing. A new study found that approximately 50% of radiologists surveyed indicated they don"t recall ever having their vision tested or it had been 24 months or longer since their last vision exam.
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Federal Appeals Court Rejects Lawsuit Against Abbott Over HIV/AIDS Drug Price Hike

Federal Appeals Court Rejects Lawsuit Against Abbott Over HIV/AIDS Drug Price Hike A federal appeals court on Tuesday rejected a lawsuit against Abbott Laboratories accusing the company "of antitrust violations over a sudden 400-percent price hike of a popular AIDS drug," the AP/ El Paso Times reports (7/7). Advocacy groups and drug benefit providers sued Abbott in 2004 alleging the "drugmaker raised the price of the HIV-fighting Norvir to stifle competition and boost sales of its own alternative, Kaletra. The company paid $10 million to settle the lawsuit and agreed to let the 9th U.S. Circuit Court of Appeals still determine if the price hike was an illegal business practice," writes AP/Minneapolis Star Tribune. A lawyer for the advocacy groups says they are still deciding whether to file an appeal (7/7). This information was reprinted from dailyreports.kff.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily U.S. HIV/AIDS Report, search the archives and sign up for email delivery at dailyreports.kff.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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