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Wistar Wins Patent For 'Universal' Flu Vaccine Tech, Seeks Development Partner
Philadelphia"s Wistar Institute has been issued U.S. patent No. 7,527,798 for a synthetic vaccine technology with the potential to be developed into a universal flu vaccine that could eliminate annual flu shots and protect against pandemics. Wistar is seeking a corporate partner to license and develop the vaccine, which has been tested in animals and currently is in prototype form. The patent pertains to technology developed by Walter Gerhard, professor emeritus and former professor of immunology at Wistar, and Laszlo Otvos, formerly an associate professor of immunology at Wistar. The vaccine prototype contains an engineered peptide that mimics a viral coat protein called M2 that remains largely constant from year to year.
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Government Of Canada Acts To Help Ensure Soft Vinyl Toys, Child-Care Articles And Other Consumer Products Are Safer
The Honourable Leona Aglukkaq, Minister of Health, announced today that the Government of Canada is proposing new regulations to prevent the use of six chemicals (phthalates) in soft vinyl toys and child-care articles. Regulations are also being proposed to further reduce lead limits in consumer products.
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Chemical In Blood May Explain Susceptibility To Bladder Pain
A marker in the blood of both cats and humans that was identified in a recent study might signal both species" susceptibility for a painful bladder disorder called interstitial cystitis, a condition that is often difficult to diagnose.
Medical Devices

Gold Treatment Relieves Pain

Many animals and people experience chronic joint pain. In dogs, a common of joint pain is hip dysplasia, a developmental defect of the hip joint. Implantation of gold into the soft tissues around the hip joints of dogs with dysplasia can relieve pain and lessen stiffness for several years. Joint pain in animals and man may be due to injury, wear or deformity. Hip dysplasia of dogs is a congenital defect that makes itself known during the growth phase, leading to varying degrees of pain and loss of function as the dogs age. Dog owners will as a rule notice that their dogs are reluctant to jump, that they lag behind on longer walks, or that they are stiff and sore when standing after resting. Some dogs also become lame after longer walks. Early in the 1970"s, an American veterinary surgeon and acupuncturist described a form of pain relief in dogs that involved implanting small grains of pure gold into acupuncture points round painful joints in dogs. The theory behind the treatment was that the gold grains implanted into the acupuncture points would provide chronic stimulation of the points. The method has been used both on dogs and people in the USA and Europe, although no scientific documentation of the pain-relieving affect of gold-implants existed. Gry Tove Jaeger has in her doctorate investigated whether grains of metallic gold implanted around painful joints could reduce pain and improve function in patients, using dogs as a model. Family dogs with pain and loss of function due to hip dysplasia were chosen as experimental animals. The dogs were divided randomly into two groups, one of which received gold transplants, while the other acted as control. Neither the owner nor the veterinarian assessing the affect of the gold treatment knew which group an individual dog belonged to. This is called double-blind experimentation. The study was designed to provide an answer to whether gold implantation had an effect or not, and any possible acupuncture effect was not considered. After six months the effect of the treatment was considered. Statistically-significant differences were shown to exist between the two groups. The dogs with implanted gold had less pain and loss of function compared to those that had not received gold. As was expected, the dogs in the control group also improved, but the effect was greater in those that had received gold. The dogs were followed for a further year and a half. After two years, 80% of the dogs still showed a positive effect of treatment. The hip dysplasia had not improved, and many dogs showed in fact an increased degree of calcification round the affected hip joints, but they lived better after the gold treatment. An inflammatory response was shown to have developed around the grains of gold, which may possibly explain in part the pain-relieving effect. Implantation of gold is an effective treatment for chronic degenerative joint disease and the method has few serious side-effects. This study could not uncover if part of the effect was due to acupuncture, to the gold lying in the soft tissue, or to a combination of the two. Cand. med. vet. Gry Jaeger defended her Ph. D. thesis, entitled "The effect of gold bead implantation in a dog model with chronic joint arthritis a method of pain control", at the Norwegian School of Veterinary Science, on May 29, 2009. Norwegian School of Veterinary Science


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