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Discovery Of Possible Drug Target For One Of The Most Aggressive Breast Cancers
Van Andel Research Institute (VARI) investigators have identified a gene that could be an important therapeutic target in the treatment of the most aggressive forms of breast cancer. Currently, patients with these cancers have few treatment options.
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Antivirals Might Be Wasted On The Elderly, Researchers Warn
A model of influenza transmission and treatment suggests that, if the current swine flu pandemic behaves like the 1918 flu, antiviral treatment should be reserved for the young. Researchers writing in the open access journal BMC Infectious Diseases found that, in this situation, providing the elderly with antiviral drugs would not significantly reduce mortality, and may lead to an increase in resistance.
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DNA Template Could Explain Evolutionary Shifts
Rearrangements of all sizes in genomes, genes and exons can result from a glitch in DNA copying that occurs when the process stalls at a critical point and then shifts to a different genetic template, duplicating and even triplicating genes or just shuffling or deleting part of the code within them, said researchers from Baylor College of Medicine in a recent report in the journal Nature Genetics. The report further elucidated the effect of the fork stalling and template switching mechanism involved in some forms of copy number variation.
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Government Of Canada Acts To Protect Newborns And Infants From Bisphenol A In Polycarbonate Plastic Baby Bottles

The Government of Canada is moving forward with proposed regulations to prohibit the advertisement, sale and importation of polycarbonate plastic baby bottles that contain bisphenol A, otherwise known as BPA, to reduce newborn and infant exposure to this substance, announced the Honourable Leona Aglukkaq, Minister of Health. BPA is used in the production of polycarbonate, a clear hard plastic used to make many products, including baby bottles. When in contact with hot or boiling liquid, bisphenol A can migrate from the plastic into the liquid and easily be ingested. "Our Government is acting to protect its most vulnerable citizens-newborns and infants," said Minister Aglukkaq. "Canada is the first country to move ahead with regulations to prohibit polycarbonate baby bottles that contain bisphenol A. We want parents to feel confident that they can safely bottle-feed their newborns and infants." The Government has concluded that exposure levels for newborns and infants up to 18 months of age are below those that could cause health effects. However, due to the uncertainty raised in some studies relating to the potential effects of low levels of BPA, the Government wants to further limit exposure. These actions are the latest measures by the Government of Canada to regulate chemicals that are harmful to human health or the environment under Canada"s world-leading Chemicals Management Plan. Health Canada has now published these proposed regulations in Canada Gazette Part I for a 75 day public comment period to consult with interested parties. Please visit the Chemical Substances website for more information on the Chemicals Management Plan. Health Canada


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