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Sleep And Weight Gain: A Molecular Link
There appears to be a link between sleep and weight control, with some studies indicating that sleep disruption can increase weight gain and others that diet affects sleep. Victor Uebele and colleagues, at Merck Research Laboratories, West Point, have now provided further evidence to support this association by showing that T-type calcium channels regulate body weight maintenance and sleep in mice. These data suggest that sleep and circadian treatment approaches may be of benefit in the fight against obesity.
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Vi Typhoid Vaccine Proves Highly Effective In Young Children
A new study has found that a currently available yet underused vaccine against typhoid fever is highly effective in young children and protects unvaccinated neighbors of vaccinees.
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Denmark Patient First To Develop Resistance To Tamiflu
A spokesperson from the vaccine manufacturer Roche confirmed reports Monday that a Denmark patient with H1N1 (swine flu) developed resistance to the antiviral Tamiflu, a drug known to decrease the spread and severity of the virus, Reuters reports (Cage/Arnold, 6/29). According to the AP/News & Observer, the patient has since recovered.
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Magee-Womens Hospital Awarded For Achievements In Reducing Elective Induced Labor

Magee-Womens Hospital of UPMC recently won a first-place achievement award from the Hospital & Healthsystem Association of Pennsylvania (HAP) in patient safety for achievements in researching and improving the process for elective induction of a woman"s labor. Dennis English, M.D., vice president of medical affairs at Magee, and a team of obstetricians and nurses led the initiative, recognizing the negative consequences of electively inducing labor upon mothers" requests. Over a 15 year period, from 1989 to 2004, elective inductions in the U.S. saw a four-fold increase, escalating from 9 percent of expectant mothers in 1989 to 21 percent in 2004. Premature or inappropriate inductions-those prior to 39 weeks gestation-can lead to complications including an increased risk of cesarean birth, longer and more complicated labor, and higher risk of admission to a neonatal intensive care unit for the newborn. To address these issues, Dr. English and his team developed stricter guidelines and criteria for electively inducing labor before the pregnancy comes to term, with only situations involving an unwell mother or infant warranting an early induction. Since the beginning of this initiative, the Magee team, with the support and cooperation of Magee"s obstetrical staff, has reduced the elective induction rate before 39 weeks gestation from 12 percent to zero. "There"s a reason why Magee is one of the nation"s leaders in women"s health care and research," Dr. English said. "We are continually looking for new ways to improve the quality of our patients" care, and this initiative is a perfect example of that commitment." The HAP awards program recognizes top health care providers that have developed innovative, adaptable projects that enhance patient satisfaction and improve health care quality, and that produce cost savings and other efficiencies. Dr. English and his team also received one of last year"s Fine Awards sponsored by The Fine Foundation and the Jewish Healthcare Foundation. The team won the first place Gold Award for its work in "Labor Induction Process Improvement." University of Pittsburgh


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