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For Women With PCOS, Acupuncture And Exercise May Bring Relief, Reduce Risks
Exercise and electro-acupuncture treatments can reduce sympathetic nerve activity in women with polycystic ovarian syndrome (PCOS), according to a new study. The finding is important because women with PCOS often have elevated sympathetic nerve activity, which plays a role in hyperinsulinemia, insulin resistance, obesity and cardiovascular disease
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Short-Timer Whitehouse Has His Say
"While Sen. Sheldon Whitehouse (D-R.I.) is expected to be on the Senate Health, Education, Labor and Pensions Committee only for a short time, he should have a major effect on health reform," Roll Call reports. "Senate Majority Leader Harry Reid (D-Nev.) chose Whitehouse to temporarily take the place of former Sen. Hillary Rodham Clinton (D-N.Y.), now secretary of State, on HELP because of his experience with health care policy at the state level." But when Sen. Al Franken, D-Minn., takes over "the long-vacant Minnesota seat, Whitehouse"s time on the committee will soon be coming to an end -- but not before the health debate is finished."
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Altair Therapeutics Reports Successful Completion Of Phase I Study Of Inhaled AIR645
Altair Therapeutics, Inc., a privately-held, biopharmaceutical company developing novel therapeutics for respiratory diseases, reported results from its phase I study evaluating the safety, tolerability and pharmacokinetics of its lead product, once-weekly inhaled AIR645, in healthy volunteers. AIR645 is a non-steroidal dual inhibitor of cellular responses to interleukin (IL)-4 and IL-13, cytokines that play a critical role in development and progression of asthma, rhinitis and other allergic disorders. Results presented today at the 2009 International Conference of the American Thoracic Society (ATS) within the Mini-Symposium "New Treatment Approaches for Asthma and Allergy" showed that inhaled AIR645 was safe, well tolerated and had dose-dependent exposure in the airways. These results demonstrate the potential of AIR645 as a convenient once-weekly treatment for asthma and other respiratory disorders. Later this year, Altair plans to initiate a phase II efficacy study in patients with asthma.
Oncology

Printing New Organs: Foundation Funds Medical Technology That Replicates Human Tissue

Methuselah Foundation has identified Organovo, Inc. as a leader in the extraordinary science of bio-printing. The US Department of Health and Human Services predicts: "Within 20 years regenerative medicine will be the standard of care for replacing all tissue/organ systems in the body." Organovo, with the support of Methuselah Foundation, is applying its breakthrough organ printing technologies to make that prediction a reality. "Methuselah Foundation, through the generosity of its donors, funds multiple strategies designed to extend healthy human life," according to Dave Gobel, Founder and CEO. The MLife Sciences program of Methuselah Foundation seeks long-term strategies to combat the progressive, degenerative process of biological aging. What is accepted as "aging" is a wide range of damage that occurs at the cellular level. Our bodies show and feel the results: functionality is lost and age-related frailty, disability and disease take over. Organovo is developing a very promising solution. Their 3-dimensional bio-printer lays down bio-ink that fuses into complex tissue, creating new tissue to replace diseased tissue. Rejection of transplanted tissue is not a concern; the cells that are used can be taken from youthful progenitor cells from the patient to replace the older diseased cells. Keith Murphy, CEO of Organovo, looks ahead, "Organovo has an exciting technology platform that has attracted broad investment at a time when capital is not free flowing. The technology has immediate applications in cardiovascular therapeutics, and as the platform of choice for three dimensional tissue development. In the future Organovo hopes to provide "Tissue on Demand" for surgical applications." Organovo, Inc. is a seed-stage regenerative medicine company that applies proprietary organ printing technology to solve critical problems in transplant medicine, cardiovascular medicine, tissue repair, and medical research. Keith Murphy, CEO of Organovo, looks ahead, "Organovo has an exciting technology platform that has attracted broad investment at a time when capital is not free flowing. The technology has immediate applications in cardiovascular therapeutics, and as the platform of choice for three dimensional tissue development. In the future Organovo hopes to provide "Tissue on Demand" for surgical applications." Organovo, Inc. is a seed-stage regenerative medicine company that applies proprietary organ printing technology to solve critical problems in transplant medicine, cardiovascular medicine, tissue repair, and medical research. Methuselah Foundation is a non-profit medical charity dedicated to extending healthy human life. The Foundation supports strategies that accelerate progress toward a comprehensive cure for age-related disease, disability, and suffering. Supported by the donations of individuals and organizations, the Foundation replaces resignation with an understanding of what is possible. Methuselah Foundation"s programs include near, mid-and long-term strategies that advance the mission of ending age-related disease through awareness, education, scientific research and direct community outreach Methuselah Foundation


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