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As The Market Potential Grows, Developers Press For Keys To Delivering Systemic Drugs Via Inhalation
At a time when the drug industry is striving for patient-friendly delivery methods for new and existing drugs, the growing availability of innovative inhaler device designs is driving interest in pulmonary drug delivery technology and devices as an alternative to oral and parenteral routes of administration. While well-established for treating upper respiratory diseases such as asthma and COPD, companies competing in the inhaled drug delivery sector - major players such as GlaxoSmithKline, AstraZeneca and Boehringer Ingelheim as well as pure-play start-ups - continue to view delivery of systemic drugs via inhalation as a major opportunity.
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Discovery Of Tiny Protein-Activator Responsible For Brain Cell Damage In Huntington Disease
Johns Hopkins brain scientists have figured out why a faulty protein accumulates in cells everywhere in the bodies of people with Huntington"s disease (HD), but only kills cells in the part of the brain that controls movement, causing negligible damage to tissues elsewhere. The answer, reported this week in Science, lies in one tiny protein called "Rhes" that"s found only in the part of the brain that controls movement. The findings, according to the Hopkins scientists, explain the unique pattern of brain damage in HD and its symptoms, as well as offer a strategy for new therapy.
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Unexpected Bacterial Diversity Found On Human Skin
The health of our skin - one of the body"s first lines of defense against illness and injury - depends upon the delicate balance between our own cells and the millions of bacteria and other one-celled microbes that live on its surface. To better understand this balance, National Institutes of Health researchers have set out to explore the skin"s microbiome, which is all of the DNA, or genomes, of all of the microbes that inhabit human skin. Their initial analysis, published in the journal Science, reveals that our skin is home to a much wider array of bacteria than previously thought.
Cardiovascular

St. Elizabeth Healthcare Drives Kentucky's Largest Electronic Medical Records Initiative With IBM

IBM (NYSE: IBM) announced that St. Elizabeth Healthcare is connecting hospitals, clinics and physicians offices in Northern Kentucky in the state"s largest roll-out of electronic medical records to improve patient care and lower costs. Today, only 1.5 percent of U.S. hospital systems have a comprehensive electronic records system putting St. Elizabeth Healthcare at the leading edge of nationwide efforts to modernize health care and meet the nation"s goal of providing every patient an electronic medical record by 2014. The system is expected to replace a warehouse full of paper-based records on more than 50,000 patients in the St. Elizabeth Healthcare system. "This represents an important step and a unified foundation to deliver better care to our patients," said Alex Rodriguez, chief information officer, St. Elizabeth Healthcare. "Today, only about one-sixth( )of the population in the US is covered by an electronic health record. This major initiative will mean that more than 12 percent of the population of Northern Kentucky and the greater Cincinnati area will have an electronic medical record. Regardless if a patient is seen at their physician"s office, an acute care hospital or the emergency room, caregivers will have deep insight into patient history and care can be better coordinated." The new system is expected to help improve the quality of care each patient receives by providing better access to patient information, a complete view of patient history, medication and treatment plans, and even faster access to lab results to make better, more informed decisions. It will make it easier for patients to obtain prescriptions electronically to reduce medical errors, cut drug costs and save doctors and patients" time and money. Patients will also be able to access their medical records, get lab results, schedule appointments and get referrals online. With the click of a mouse, doctors and nurses will be able to see real-time patient information, lab results, EKGs, x-rays, scans and even prescriptions, making it faster and easier to make a more effective diagnosis and treatment plan. Plans for this new integrated system were underway before the federal government turned its focus to electronic medical records as part of economic stimulus efforts. However, the new EMR system at St. Elizabeth Healthcare meets the requirements for hospitals and doctor"s offices and is well-positioned to meet all criteria for stimulus funds. The Congressional Budget Office estimates that mass adoption of systems such as this one could result in savings of $12 billion over 10 years. The roll out of the new system is focused first on doctor"s offices which will begin in September, and then clinics and ambulatory care sites within St. Elizabeth Healthcare. The entire system including all six hospitals, nearly 1,000 physicians, 31 primary care doctor"s offices and four imaging centers and clinics is expected to be fully connected in one unified system by fall 2010. This system uses Epic"s software and is powered by IBM Power 570 and 550 servers running AIX, IBM"s UNIX operating system. The medical records and clinical information system includes EpicCare Ambulatory, Resolute Hospital Billing, EpicCare Inpatient, Prelude Registration and Cadence Scheduling. IBM Power Systems servers with virtualization technology provide the advanced computing power to support the system, and offer the flexibility to expand as the hospital system"s needs grow. IBM Power Systems servers provide St. Elizabeth Healthcare with increased scalability and improved performance over other server technologies that were considered. IBM is creating a smarter, more connected healthcare system that delivers better care with fewer mistakes, predicts and prevents diseases, and empowers people to make better choices. This includes integrating data so doctors, patients and insurers can share information seamlessly and efficiently. IBM also helps clients apply advanced analytics to improve medical research, diagnosis and treatment in order to improve patient care and help reduce healthcare costs. IBM


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