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Sciele Pharma Announces Availability Of Ulesfia (Benzyl Alcohol Lotion 5%), First Prescription Non-Neurotoxic Head Lice Treatment
Sciele Pharma, Inc., a Shionogi Company, announced the availability of Ulesfia (Benzyl Alcohol Lotion 5%), the first and only prescription medication that kills head lice by asphyxiation without potential neurotoxic side effects. Approved by the U.S. Food & Drug Administration (FDA), Ulesfia is indicated for the topical treatment of head lice infestation in patients 6 months of age and older. Ulesfia is available now by prescription nationwide in time for peak head lice season.
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DNA Template Could Explain Evolutionary Shifts
Rearrangements of all sizes in genomes, genes and exons can result from a glitch in DNA copying that occurs when the process stalls at a critical point and then shifts to a different genetic template, duplicating and even triplicating genes or just shuffling or deleting part of the code within them, said researchers from Baylor College of Medicine in a recent report in the journal Nature Genetics. The report further elucidated the effect of the fork stalling and template switching mechanism involved in some forms of copy number variation.
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'Taking Up A Dialogue' With The Brain: Letter Decoding From Single-trial Brain Signals
Brain-computer interfaces "translate" what a person is thinking in words or actions. Researchers from Maastricht University in the Netherlands performed functional MRI brain scans on healthy participants, instructing them to "type" by performing mental tasks corresponding to different letters in the English alphabet. Researchers were able to use signals from the participants" brain activation patterns to decode information about the intended letter that a participant was thinking about, and to use this in a conversation with the experimenters without any spoken words. It is hoped that such technology can enable communication with "locked-in" patients or assessment of consciousness in non-responsive patients.
Cardiovascular

U.S. Decision On Use Of Adjuvants Could Reduce World Supply Of H1N1 Vaccine, Says Lancet Editorial

"A U.S. plan to rely on swine flu vaccines without ingredients to stretch the supply [known as adjuvants] would reduce the number of available shots just when other countries need them most, the British journal Lancet said in an editorial," Bloomberg writes. On July 7, the WHO recommended the use of adjuvants - "mixes of oil and water that trigger a stronger response in the body to antigen, the substance that induces immunity" - to increase the global vaccine supply. Though adjuvants are not approved for flu vaccines in the U.S., HHS" decision to declare the H1N1 flu a public health emergency in April gave the FDA the go-ahead to use "unapproved medical products including adjuvants," according to Bloomberg. Acknowledging that the global manufacturing of the H1N1 vaccine will not be able to meet worldwide demand, the editorial authors write, "The USA must support the use of dose-sparing strategies to avoid depletion of an already short vaccine supply." The article includes comments by HHS spokesman Bill Hall about future plans in the U.S. to test the safety and effectiveness of adjuvants, and says, "The additives may not be necessary if enough shots can be produced without them, HHS officials said. Authorities at the CDC said July 29 that 40 million shots of unadjuvanted vaccine may be available to the U.S. in September, earlier than previously reported, with 80 million more doses ready in October" (Randall, 7/31). The Lancet editorial also appeals for countries to "assess carefully the risks and benefits of rapid approval of an H1N1 vaccine, especially since the disease has so far been mild with most patients making a full recovery. They must also ensure that they have strong post-marketing surveillance in place before rolling out a vaccine" (8/1). This information was reprinted from globalhealth.kff.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Global Health Policy Report, search the archives and sign up for email delivery at globalhealth.kff.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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